Description
Low Dose Naltrexone (LDN) Compounded Capsule
Naltrexone is an FDA-approved medication that, at standard doses ($50\text{ mg}$ to $100\text{ mg}$), is used to treat opioid and alcohol dependence. However, when prescribed at micro-doses—typically ranging from $1.5\text{ mg}$ to $4.5\text{ mg}$—it acts as Low Dose Naltrexone (LDN).Because commercial manufacturers only produce Naltrexone in high-dose tablets, obtaining a true low-dose format requires a compounding pharmacy. Our Compounded LDN Capsules are meticulously formulated to deliver these exact, ultra-low milligram strengths. At this fraction of the standard dose, LDN serves an entirely different therapeutic purpose, offering a unique mechanism that helps regulate the immune system and modulate chronic pain.
Our compounding pharmacists utilize high-precision scales to ensure exact dosing accuracy for your specific titration schedule.
- Active Ingredient: Naltrexone Hydrochloride (custom low-doses, typically 0.5mg, 1.5mg, 3.0mg, or 4.5mg).
- Dosage Form: Oral capsules designed for easy daily compliance.
- Hypoallergenic Fillers: Commercial tablets often contain binders that trigger sensitivities.
We compound our LDN capsules using clean, inactive fillers (like sucrose or microcrystalline cellulose) and completely avoid common irritants like gluten, lactose, and artificial dyes.
Because LDN functions by interacting with your body’s opioid receptors, it has unique drug interactions that must be carefully managed. Please consult your physician regarding:
- Opioid Pain Medications (e.g., Tramadol, Oxycodone, Morphine): LDN will block the efficacy of narcotic pain relievers and can trigger sudden, severe withdrawal symptoms. Patients must be fully off opioids before starting LDN.
- Immunosuppressants (e.g., Prednisone, Humira): Because LDN modulates the immune system, taking it alongside heavy immunosuppressive therapies requires close monitoring by your specialist.
LDN works by binding to opioid receptors in the body for a very brief window—usually just a few hours. This temporary blockade tricks the body into thinking it is low on endorphins (your natural pain-relieving chemicals).
In response, the body triggers a rebound effect, increasing the production of both endorphins and opioid receptors. This natural boost helps down-regulate inflammation, calms overactive immune cells (microglia) in the central nervous system, and alters pain signaling pathways. Because the capsule is taken orally (typically at bedtime), it supports the body’s natural healing and immune regulating cycles while you sleep.
While standard Naltrexone addresses addiction, Low Dose Naltrexone capsules are widely prescribed off-label to support patients dealing with chronic, hard-to-treat inflammatory and autoimmune conditions:
- Fibromyalgia & Chronic Fatigue Syndrome (ME/CFS): Helping reduce systemic neuroinflammation and widespread muscle pain.
- Autoimmune Support: Routinely utilized as an adjunctive therapy for Hashimoto’s thyroiditis, Multiple Sclerosis (MS), and Crohn’s disease.
- Chronic Pain Management: Offering a non-addictive alternative for complex regional pain syndromes.
Can’t I just buy the 50 mg tablet and dissolve or split it myself?
Attempting to split a 50mg tablet down to micro-doses at home is highly inaccurate and dangerous, as the active drug is not evenly distributed across the tablet binders. Compounded capsules guarantee a precise, laboratory-verified micro-dose in every single pill.
Is your pharmacy licensed for Texas delivery?
Yes. We are fully compliant with Texas State Board of Pharmacy regulations and ship custom LDN capsule orders exclusively to patients throughout the state of Texas.

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