Description
Compounded Lidocaine 5% / Nifedipine 0.5% Ointment
Lidocaine 5% / Nifedipine 0.5% Ointment is a specialized topical formulation frequently used in proctology and dermatology to manage symptoms associated with localized pain and discomfort. This combination pairs a local anesthetic with a calcium channel blocker to provide dual-action support.
By compounding these two active ingredients into a single, smooth ointment base, pharmacists can provide a customized concentration that addresses discomfort at the site of application.
Our compounding pharmacy prepares this non-sterile ointment using pharmaceutical-grade active ingredients, ensuring the mixture is homogeneous and optimized for topical absorption.
- Lidocaine (5%): A local anesthetic that works by temporarily blocking nerve signals in the skin, providing localized relief from pain and itching.
- Nifedipine (0.5%): A calcium channel blocker that, when applied topically, helps promote the relaxation of smooth muscle tissue in the affected area, which can assist in relieving discomfort and supporting natural healing.
- Dosage Form: Topical ointment.
- Quality Commitment: Each batch is prepared according to standardized compounding protocols to ensure the medication is properly dispersed within the ointment base for consistent, even application.
The synergistic combination of these two agents targets pain through different pathways:
- Analgesic Effect: Lidocaine provides immediate, temporary relief from surface pain and discomfort by stabilizing neuronal membranes.
- Smooth Muscle Relaxation: Nifedipine acts as a vasodilator. When applied topically, it helps relax the smooth muscle, which may reduce tension or spasms in the localized area, thereby addressing the underlying source of discomfort.
This topical medication is intended for external use only. Please consult your physician regarding the following:
- Systemic Absorption: While formulated for local effect, some absorption into the bloodstream can occur. Patients with a history of low blood pressure or heart conditions should discuss the use of Nifedipine with their provider.
- Allergy Awareness: Discontinue use and contact your healthcare provider immediately if you experience signs of an allergic reaction, such as increased redness, rash, or irritation at the application site.
- Application Guidance: Use only as directed by your healthcare provider. Do not apply to broken, infected, or severely irritated skin unless specifically instructed by your physician.
How should this ointment be applied?
Apply the ointment as directed by your healthcare provider. Typically, a small amount is applied to the affected area. Always wash your hands thoroughly before and after application.
Is this a sterile preparation?
This is a non-sterile compounded preparation intended for topical, non-mucosal, or specific dermatological use as prescribed. It is prepared in a clean environment following standard pharmacy compounding safety protocols.
Do you ship this product across Texas?
Yes. We are fully compliant with Texas State Board of Pharmacy regulations and securely ship all compounded ointment orders exclusively to patient addresses located within the state of Texas.

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