Custom Compounded Progesterone Pellet

Because hormone pellets are implanted directly into vascular subcutaneous tissue, maintaining absolute sterility is a non-negotiable medical requirement. Our pharmacy compounds these implants within a state-of-the-art cleanroom that strictly complies with USP sterile compounding standards, ensuring every pellet is completely free of contaminants.

Active Ingredient: High-purity, bioidentical Progesterone.

Available Strengths: Formulated in both 50 mg and 100 mg cylinders.

Preparation Type: Sterile subcutaneous solid implant.

Quality Testing: Every production lot undergoes rigid quality verification, including mandatory independent sterility testing, weight-checked density validation, and endotoxin screening before clinical use.

Progesterone pellets function by establishing a steady-state equilibrium with your body’s circulatory network:

Continuous Capillary Absorption: Once implanted, the body forms a microscopic capillary network around the pellet. As cardiac output moves blood across this network, the pellet slowly dissolves, transferring progesterone directly into the bloodstream.

Eliminating First-Pass Metabolism: Bypassing the stomach and liver prevents the hormone from being prematurely converted into metabolic down-products, maintaining a cleaner, more reliable active hormone profile.

Endometrial Protection: For patients undergoing concurrent estrogen therapy, a steady release of progesterone is vital to protect the lining of the uterus (endometrium) from unmitigated cellular growth.

Pellet therapy requires a simple in-office medical procedure performed under sterile conditions by a licensed medical practitioner.

The Insertion Procedure: The doctor uses a local anesthetic to numb a small area on the hip or upper buttocks. A tiny incision is made, the 50 mg or 100 mg pellets are deployed into the subcutaneous fat layer, and the site is sealed with medical closure strips.

Post-Implant Care: Keep the insertion site clean and completely dry for 3-5 days following the procedure. Avoid vigorous lower-body exercise, heavy lifting, or soaking in hot tubs or pools until the incision has fully closed to minimize infection risks.

Clinical Surveillance: Your provider will order periodic serum hormone labs (blood tests) to ensure your systemic progesterone levels remain safely balanced within your targeted therapeutic window.

What is the advantage of a 50 mg or 100 mg pellet over oral progesterone?

Oral progesterone must pass through your liver, which breaks down a significant portion of the active medicine and can cause next-day drowsiness. Pellets deliver a controlled, uniform micro-dose directly to your blood vessels 24 hours a day, preventing hormone spikes and eliminating daily dosing compliance issues.

How long do these pellets take to dissolve completely?

Because of the steady density achieved during our sterile compounding process, progesterone pellets typically dissolve slowly and provide stable hormone support for approximately 3 to 5 months, depending on your body’s specific metabolic rate.

Do you ship these sterile implants to providers or clinics outside of Texas?

No. In strict accordance with the Texas State Board of Pharmacy licensing frameworks and state regulations, we fulfill, verify, and ship all sterile compounded Progesterone pellets exclusively to medical facilities or patient locations within the state of Texas.